Toxicology & Medication Monitoring
All of Our Solutions Help Provide Medical Necessity & Support Regulatory Compliance
- Improves physician’s ability to manage or change therapy with prescription drugs.
- Aids physician’s ability to avoid potentially dangerous drug interactions.
- Offers patients and physicians greater protection from drug abuse and diversion.
- Allows for physician confidence in prevention of medication addiction or relapse.
Toxicology Testing Process
We provide accurate Urine Drug Testing (UDT) for prescription, recreational, and illicit drugs as well as alcohol and nicotine. This is important for individuals, employers, and physicians. The laboratory uses highly-sensitive UDT and oral fluids testing technology to ensure reliable results through screening and confirmatory testing.
The screening test uses an immunoassay to look for the parent drug and/or metabolite. If a confirmatory test is required, it will be ran through liquid chromatography/tandem-mass spectrometry (LC/MS/MS); the confirmatory test is very specific and is typically used when testing for the presence of a specific drug is needed. The methodology to obtain confirmation depends on the type of drug being tested.
The first step of a 2-step confirmatory process
- Grouped by class of drug: Amphetamines, Barbiturates, Benzodiazepines, Cocaine, Cannabinoids, Oxycodone, Opiates, Methadone, Buprenorphine, PCP, and Ethanol
- Initial immunoassay screen reports qualitative results (positive or negative) based on established cutoff concentrations.
Liquid Chromatography Tandem-Mass Spectrometry – LC-MS/MS
A confirmatory test that is performed as the second step of a 2-step process.
- Level of sensitivity and specificity is significantly greater than immunoassays due to a lower cut-off value (ng/ml).
- LC-MS/MS detects compound specific individual drugs in patient samples.
- We test for parent drugs (ex: Hydrocodone) and for metabolites (ex: Hydromorphone). This allows for better interpretation of patient’s medication and/or illicit drug use.
- This testing method is the most sensitive and specific to help exclude false positive results.
- Used to confirm positive results.